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Retinoic acid

INCI Name

:

Retinoic Acid

Chemical Name /Synonyms

:

Tretinoin; all-trans-Retinoic acid; Vitamin A acid; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid

CAS No.

:

302-79-4

EINECS

 

206-129-0

Molecular Formula

:

C20H28O2

Molecular Weight

:

300.44

Structure

:

 

 

 

 


Action and Application

1.  Treatment of acne

2.  Reduce pigmentation

Inhibit tyrosinase induction, interfere with pigment transfer, accelerate epidermal turnover, disperse pigment granules within keratinocytes. Act as penetration enhancers when used with other lightening agents.

3.  Treatment of melasma


Use Level:  0.01-0.1%


Specification

 

Appearance

:

Yellow or light orange crystalline powder

 

Solubility

:

Conforms

 

Melting point

:

Almost 182℃

 

Identification

:

Conforms

 

Loss on drying

:

≤0.5%

 

Ignition residue

:

≤0.1%

 

Heavy metals

:

≤0.002%

 

Isotretinoin

:

≤5%

 

Relevant substance

:

≤0.5%

 

Residual Solvent

:

Conforms

 

Assay

:

98.0-103.0%



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